Secondary alcohol dehydrogenase enzyme and use thereof
US4241184A · kind A · utility
8Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1979 |
| Grant date | Dec 23, 1980 |
| Priority date | — |
| Expiry date | Mar 27, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/858
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a newly-discovered and isolated enzyme which is a nicotinamide adenine dinucleotide (NAD.sup.+)-linked C.sub.3 -C.sub.6 secondary alcohol-specific dehydrogenase. This enzyme, in the presence of oxygen and NAD, is capable of converting C.sub.3 -C.sub.6 secondary alcohols to the corresponding methyl ketones. The purified enzyme has a molecular weight of 95,000 .+-. 3,000 dalton as determined by acrylamide gel electrophoresis and contains two zinc atoms per molecule of protein. Primary alcohols are not oxidized by this enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.