Quinoxalinones useful for treating atopic eczema and urticaria
US4242342A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 31, 1979 |
| Grant date | Dec 30, 1980 |
| Priority date | — |
| Expiry date | May 31, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/495
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula below are useful for expanding the lumina of air passages in a mammal in need of said treatment. The compounds are also useful for treating atopic eczema and urticaria. ##STR1## wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, nitro, trifluoromethyl, alkyl of one to four carbon atoms, inclusive, alkoxy of one to four carbon atoms, inclusive, and cyano; PA0 R.sub.1 is hydrogen, methyl or ethyl; PA0 R.sub.2 is hydrogen, alkyl of one to six carbon atoms, inclusive, phenyl, benzyl, PA0 CH.sub.2 Z wherein Z is fluoro, chloro, or bromo, PA0 CO.sub.2 M, CH.sub.2 CO.sub.2 M, CH.sub.2 CH.sub.2 CO.sub.2 M and CHR.sub.3 CO.sub.2 M wherein M is hydrogen, alkyl of one to four carbon atoms, inclusive, or a physiologically acceptable metal or amine cation and R.sub.3 is alkyl of one to three carbon atoms, inclusive, with the proviso that M is not hydrogen when R.sub.2 is CH.sub.2 CO.sub.2 M or CHR.sub.3 CO.sub.2 M.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.