9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
US4243674A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 12, 1978 |
| Grant date | Jan 6, 1981 |
| Priority date | — |
| Expiry date | Jun 12, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
9-Hydroxydibenzo[b,d]pyrans useful as analgesics, hypotensives, immunosuppressants, tranquilizers; as anti-secretory and anti-anxiety drugs; intermediates therefor and derivatives thereof having the formulae ##STR1## wherein R is hydrogen or alkanoyl having from one to five carbon atoms; PA1 R.sub.1 is hydrogen, alkanoyl having from one to five carbon atoms or --CO--(CH.sub.2).sub.p --NR.sub.2 R.sub.3 wherein p is 0 or an integer from 1 to 4; each of R.sub.2 and R.sub.3 when taken individually is hydrogen or alkyl having from one to four carbon atoms; R.sub.2 and R.sub.3 when taken together with the nitrogen to which they are attached form a 5- or 6-membered heterocyclic ring selected from piperidino, pyrrolo, pyrrolidino, morpholino and N-alkylpiperazino having from one to four carbon atoms in the alkyl group; PA1 each of R.sub.4 and R.sub.5 is hydrogen, methyl or ethyl; PA1 R.sub.0 is oxo or alkylenedioxy having from two to four carbon atoms; PA1 Z is PA2 (a) alkylene having from one to nine carbon atoms; PA2 (b) --(alk.sub.1).sub.m --X--(alk.sub.2).sub.n -- wherein each of (alk.sub.1) and (alk.sub.2) has from 1 to 9 carbon atoms, with the proviso that the summation of carbon ato…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.