Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
US4243681A · kind A · utility
6Cited by
14References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 16, 1979 |
| Grant date | Jan 6, 1981 |
| Priority date | — |
| Expiry date | Apr 16, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D303/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A new class of alkylthiophenoxypropanolamine derivatives and methods for preparation are described. The compounds have vasodilating and antispasmodic activity, inhibit blood platelet aggregation and are substantially free of beta-adrenergic blocking effects. They are particularly valuable in the treatment of disease states responsive to vasodilation such as obstructive peripheral vascular diseases and cerebral vascular deficiencies. A representative and preferred embodiment of the invention consists of 1-[4-(1-methylethylthio)phenoxy]-3-(octylamino)-2-propanol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.