Triazinones

US4246409A · kind A · utility

Assignee

• William H. Rorer, Inc. · US

Inventors

• George H. Douglas · Paoli, US
• William L. Studt · Harleysville, US
• Chong M. Won · Warrington, US
• Stuart A. Dodson · Lansdale, US
• Jerome J. Zalipsky · Melrose Park, US

Key dates

• Filing date: Nov 13, 1978
• Grant date: Jan 20, 1981
• Expiry date: Nov 13, 1998

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thiones are useful derivatives in analyzing for the corresponding amidinourea or amidino thiourea precursors and also have useful pharmacological properties which make them suitable for a variety of medicinal purposes including use as antidiarrheal agents.