Patent · US Expired

Ansamycin antibiotic

US4247462A · kind A · utility

4Cited by

1References

1Claims

0Family size

Assignee

PFIZER INC. · US

Inventors

Walter D. Celmer · New London, US
Walter P. Cullen · East Lyme, US
John R. Oscarson · Pawcatuck, US
Liang H. Huang · Mesa, US
Riichiro Shibakawa · Handa, JP
Junsuke Tone · Chita, JP

Key dates

Filing date	Jan 3, 1980
Grant date	Jan 27, 1981
Priority date	—
Expiry date	Jan 3, 2000

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/465
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A new subspecies of Streptomyces nigellus Prokop, designated Streptomyces nigellus Prokop subsp. africanus Huang subsp. nov. ATCC 31496, when propagated under aerobic conditions in aqueous nutrient media, produces a mixture of antibiotics. One of these antibiotics is the known macrolide antibiotic cirramycin A; the ansamycin antibiotic is an analogue of protostreptovaricin and the structure has been established as 21-hydroxy, 25-demethyl, 25-methylthioprotostreptovaricin I.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.