Organic compounds
US4247543A · kind A · utility
2Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1979 |
| Grant date | Jan 27, 1981 |
| Priority date | — |
| Expiry date | Apr 9, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides polypeptides of the formula, EQU A-B-Gly-D-E-F wherein PA0 A is Tyr or substituted Tyr, PA0 B is, for example, -Gly-, -(D)-Ala-, or -(D)-Met-, PA0 D is Phe or substituted Phe, PA0 E is, for example, -Leu-, -Nle-, -Nva-, -Ile- or -Val-, PA0 and F is -NR.sub.7 CHR.sub.8 CH.sub.2 OR.sub.3 ', PA1 wherein, for example, R.sub.3 ' may be hydrogen or alkyl--CO--, R.sub.7 is hydrogen or alkyl and R.sub.8 is alkyl, which compounds possess pharmacological activity, for example, analgesic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.