Process for the preparation of 5-substituted resorcinols and related intermediates
US4249027A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 1, 1976 |
| Grant date | Feb 3, 1981 |
| Priority date | — |
| Expiry date | Nov 1, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C37/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
According to the present invention, 5-substituted resorcinols of the formula I ##STR1## wherein R.sub.1 represents a hydrocarbon radical, optionally unsubstituted or substituted by inert substituents, are prepared by reacting a carboxylic acid ester of the formula II EQU R.sub.1 --C.tbd.C--CO--O--R.sub.2 (II) wherein R.sub.2 represents a non-aromatically bound lower hydrocarbon radical, in the presence of an alkaline condensation agent, with a diester of 3-oxoglutaric acid of the formula III EQU R.sub.3 --O--CO--CH.sub.2 --CO--CH.sub.2 --CO--O--R.sub.4 (III) wherein R.sub.3 and R.sub.4 represent non-aromatically bound lower hydrocarbon radicals; hydrolyzing the resulting dihydroxyisophthalic acid acid ester of the formula IV ##STR2## and decarboxylating the hydrolyzed product, a specific embodiment is the preparation of 5-pentylresorcinol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.