Bioerodible system for delivering drug manufactured from poly(carboxylic acid)
US4249531A · kind A · utility
192Cited by
13References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 5, 1979 |
| Grant date | Feb 10, 1981 |
| Priority date | — |
| Expiry date | Jul 5, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M31/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A device for the controlled continuous administration of an active agent to an environment of use is disclosed. The device comprises a body of erodible agent release rate controlling material containing an agent dispersed therethrough; the rate controlling material is a hydrophobic poly(carboxylic acid) having one ionizable carboxylic hydrogen for each 8 to 12 carbon atoms, which material erodes at a controlled and continuous rate over a prolonged period of time in response to the environment by a process of carboxylic hydrogen ionization, thereby releasing the dispersed agent at a controlled rate over a prolonged period of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.