Patent · US Expired

Method of slowing heart rate

US4250186A · kind A · utility

4Cited by

5References

1Claims

0Family size

Assignee

Boehringer Ingelheim GmbH · DE

Inventors

Helmut Stahle
Herbert Koppe · Ingelheim am Rhein, DE
Werner Kummer · Ingelheim am Rhein, DE
Wolfgang Hoefke · Wiesbaden, DE
Wolfram Gaida · Ingelheim am Rhein, DE
Ludwig Pichler · Wien, AT

Key dates

Filing date	Feb 16, 1979
Grant date	Feb 10, 1981
Priority date	—
Expiry date	Feb 16, 1999

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P9/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein R is 2-bromo-4,5-dihydroxy-phenyl; 3-chloro-4-hydroxy-phenyl; 4-bromo-2,5-dihydroxy-phenyl; 3,5-dihydroxy-phenyl; 5-chloro-2,4-dihydroxy-phenyl; 3-hydroxy-4-methyl-phenyl; 2,6-dibromo-4-hydroxymethyl-phenyl; 3,5-dibromo-4-amino-phenyl; 3-methylmercapto-phenyl; 3,4,5-trihydroxy-phenyl; or 3-bromo-4-fluoro-phenyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.