Patent · US Expired

Immobilized biological material

US4250267A · kind A · utility

16Cited by
7References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 1977
Grant dateFeb 10, 1981
Priority date
Expiry dateNov 10, 1997

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/80
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.