Unsaturated or substituted methyl ethers having antibiotic activity
US4251517A · kind A · utility
2Cited by
8References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 27, 1979 |
| Grant date | Feb 17, 1981 |
| Priority date | — |
| Expiry date | Jun 27, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The antibiotics Papulacandin A and Papulacandin B are etherified at the phenolic groups in positions 10 and/or 12 by introducing a group EQU --CH.sub.2 --K wherein K is a hydrocarbon radical which is either unsaturated and aliphatic, or it is saturated or unsaturated and substituted by cyclic hydrocarbons, such as aromatic or heterocyclic ones, or by functional groups, such as halogens, carboxyl groups, carboxyl ester or amide groups. These ethers are characterized by a good antifungal action e.g. against Candida albicans and also by an antifiral action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.