.beta.-Lactam antibacterial agents, their use in pharmaceutical compositions, the process for their preparation and intermediates for use in that process
US4252808A · kind A · utility
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1References
10Claims
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Assignee
Inventor
Key dates
| Filing date | Feb 26, 1979 |
| Grant date | Feb 24, 1981 |
| Priority date | — |
| Expiry date | Feb 26, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D205/095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the formula (I): ##STR1## wherein R.sup.1 is a hydrogen atom, a trityl group or an acyl group as found in known antibacterially active penicillins or cephalosporins; R.sup.2 is a hydrogen atom, a lower alkyl group or an aryl group; R.sup.3 is a hydrogen atom, a lower alkyl group, a substituted lower alkyl or a thiosubstituted lower alkyl group; and R.sup.4 is a group such that CO.sub.2 R.sup.4 is a carboxylic acid group or a salt or readily removable ester thereof; are antibiotics. The compounds may be formulated in pharmaceutical compositions. Processes for the preparation of the compounds (I) are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.