Pharmaceutical tablet composition

US4254099A · kind A · utility

Assignee

• BEIERSDORF AG · DE

Inventors

• Bodo Asmussen · Bendorf, DE
• Georg A. Ulex · Moorrege, DE

Key dates

• Filing date: Oct 1, 1979
• Grant date: Mar 3, 1981
• Expiry date: Oct 1, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/2009
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A pharmaceutical tablet composition for oral administration is disclosed which provides for accelerated release <> of a finely divided active ingredient contained therein which is only slightly soluble < in the gastrointestinal tract of a warm-blooded animal >. The tablet composition is characterized as containing a micro-dispersed, amorphous, porous silica having a primary particle size of between about 1 and 15 .mu.m, a BET surface of between about 350 and 450 m.sup.2/ g, and a pore volume of between about 1.4 and 1.7 ml/g. A method of producing the tablet composition is also disclosed.