2-Adamantyl hydrazines and biocidal compositions thereof
US4254128A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 22, 1978 |
| Grant date | Mar 3, 1981 |
| Priority date | — |
| Expiry date | Nov 22, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides novel 2-adamantyl hydrazine derivatives of the general formula A ##STR1## In this formula R.sub.1 is hydrogen or a lower alkyl group of 1-4 carbon atoms; R.sub.2 and R.sub.3 are the same or different and are each hydrogen, an unsubstituted or substituted radical being a lower alkyl of 1-4 carbon atoms, a lower alkanoic acid radical of 2-4 carbon atoms or a lower alkyl ester thereof, adamantyl, aryl, aralkyl, in which the alkyl moiety has from 1-4 carbon atoms or an unsubstituted or substituted heterocyclic radical of aromatic character; or R.sub.2 and R.sub.3 together with the nitrogen atom to which they are attached form an unsubstituted or substituted non-aromatic cyclic radical. The invention further provides pharmaceutically acceptable acid addition salts of the above compounds. Several methods of preparation of the new compounds are described. The novel compounds according to the invention possess valuable antifungal (human and plant), antiviral, antiprotozoal and antimicrobial properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.