Substituted benzonitriles having antiviral activity
US4254144A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 25, 1980 |
| Grant date | Mar 3, 1981 |
| Priority date | — |
| Expiry date | Jan 25, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C317/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted benzonitriles are disclosed having the formula ##STR1## wherein X represents O or S; R.sub.1 represents bromo, chloro, fluoro, phenoxy, loweralkylthio, loweralkylsulfinyl, loweralkylsulfonyl, loweralkylaminosulfonyl, diloweralkylaminosulfonyl or benzoyl; and R.sub.2 represents hydrogen, bromo, chloro or fluoro with the proviso that R.sub.2 is hydrogen when R.sub.1 is a substituent other than bromo, chloro or fluoro. The compounds of the invention exhibit antiviral activity. Methods of use based on the antiviral activity of the compounds are also disclosed, as well as compositions which comprise a carrier in combination with a suitable antiviral active compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.