Reagent and test kit for determining glycosylated hemoglobin
US4255385A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 23, 1979 |
| Grant date | Mar 10, 1981 |
| Priority date | — |
| Expiry date | Oct 23, 1999 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/723
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method, reagent and test kit for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.