(+)-(3-Methyl-4-oxo-5N-piperidinothiazolidin-2-ylidene)acetic acid esters, method of preparation and use

US4255433A · kind A · utility

Assignee

• Godecke Aktiengesellschaft · DE

Inventors

• Wolfgang Herrmann · Gothenburg, SE
• Gerhard Satzinger · Denzlingen, DE
• Manfred Herrmann
• Wolfgang Steinbrecher · Gundelfingen, DE
• Heinrich Bahrmann · Kirchzarten, DE

Key dates

• Filing date: Mar 21, 1980
• Grant date: Mar 10, 1981
• Expiry date: Mar 21, 2000

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention discloses (+)-(3-methyl-4-oxo-5N-piperidinothiazolidin-2-ylidene)acetic acid esters and a process for their preparation. The process provides the dextrorotatory isomers substantially free from the corresponding levorotatory isomers. Antihypertensive pharmaceutical compositions comprising the dextrorotatory esters and methods for using said compositions are also disclosed.