.beta.-Lactam antibiotics, a process for their prepaeration and their use in pharmaceutical compositions
US4255441A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1979 |
| Grant date | Mar 10, 1981 |
| Priority date | — |
| Expiry date | Jan 19, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D477/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides the antibacterial agents of the formula (II): ##STR1## wherein R.sub.1 is a group such that CO.sub.2 R.sub.1 is a carboxylic acid group or a salt thereof or is a group of the formula CO.sub.2 R.sub.1.sup.1 wherein R.sub.1.sup.1 is a group such that CO.sub.2 R.sub.1.sup.1 is an ester group, R.sub.2 is a hydrogen atom or a lower alkyl group; R.sub.3 is a hydrogen atom or a lower alkyl group; and R.sub.4 is a NH. CO.sub.n R.sub.6 group where R.sub.6 is a lower alkyl group, a phenyl group or a phenyl group substituted by one or two halogen atoms, lower alkyl or lower alkoxyl groups; and n is 1 or 2. A process for their preparation and their use in pharmaceutical compositions is also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.