New prostane derivatives and process for their preparation

US4256745A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Werner Skuballa · Berlin, DE
• Bernd Raduchel · Berlin, DE
• Helmut Vorbruggen
• Walter Elger · Berlin, DE
• Olaf Loge
• Eckehard Schillinger · Berlin, DE

Key dates

• Filing date: Mar 2, 1978
• Grant date: Mar 17, 1981
• Expiry date: Mar 2, 1998

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D309/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Prostan-1-ol esters and intermediates for their preparation are described; the former compounds exhibit improved organ specificity and a longer duration of activity at lower dosages than the corresponding non-esterified prostaglandins and are useful, inter alia, in triggering abortion, inducing labor and regulating the menstrual cycle.