Prostaglandin derivatives of the .DELTA.2,4-11-deoxy-PEG series
US4258057A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 5, 1979 |
| Grant date | Mar 24, 1981 |
| Priority date | — |
| Expiry date | Jul 5, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/535
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel prostaglandin derivatives of the formula I ##STR1## which are structurally related to the naturally occurring prostaglandins and in which R.sup.1 denotes (a) hydrogen or a straight-chain or branched, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon radical having up to ten carbon atoms or (b) a physiologically acceptable metal or NH.sub.4 ion or an ammonium ion which is derived from a primary, secondary or tertiary amine and R.sup.2 denotes a straight-chain, aliphatic hydrocarbon radical having up to six carbon atoms and to a process for their manufacture. The compounds of the invention are distinguished in particular by gastric acid secretion-inhibiting and ulcer-protective properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.