Sulfur-containing benzimidazole derivatives
US4259344A · kind A · utility
8Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 1979 |
| Grant date | Mar 31, 1981 |
| Priority date | — |
| Expiry date | Jun 22, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D235/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of anthelmintic compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen or --COOR; PA1 R.sup.5 is C.sub.1 to C.sub.4 alkyl; PA1 R.sup.2 is halogen, alkyl, trifluoromethyl, alkoxy, aryloxy, or aralkoxy; and PA1 R.sup.4 is hydrogen, alkyl, cycloalkyl; alkenyl, alkynyl or aralkyl; or pharmaceutically acceptable salts thereof comprises subjecting a bis compound of the formula: ##STR2## to reduction to cleave the disulfide linkage and where R.sup.4 is other then hydrogen, subsequent reaction of the mercapto group. Intermediate compounds and a process for preparing same are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.