2-Methyl-2-phenoxy-propionic acid derivatives, process for their preparation and therapeutical applications thereof
US4259509A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1978 |
| Grant date | Mar 31, 1981 |
| Priority date | — |
| Expiry date | Feb 2, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to compounds having the formula: ##STR1## which represents the isomer Z, the isomer E or the mixture of both stereoisomers of the oximino group and in which: PA0 A represents O or S, PA0 X.sup.1 represents a halogen atom, a hydrogen atom or a methyl group, PA0 R represents a hydrogen atom or a C.sub.1-5 alkyl group, PA0 X.sup.2 and X.sup.3, which may be the same or different, represent each a hydrogen atom, a halogen atom or a C.sub.1-5 alkyl group, and PA0 R' represents a hydrogen atom or a C.sub.1-5 alkyl group, and PA0 the group ##STR2## is at 2- or 3-position on the heterocycle, and the salts of acids of the formula (I) with physiologically acceptable bases, and the compounds which are metabolically converted to compounds of the formula (I). Said compounds are therapeutically useful, typically as hypocholesterolemic, hypolipemic and uricosuric agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.