3-Amino-4-phenyl-6-piperidino-1H-pyrazolo[3,4-b]-pyridines and salts thereof

US4260621A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Josef Roch · Biberach, DE
• Erich Muller · Zell am Harmersbach, DE
• Berthold Narr · Biberach, DE
• Josef Nickl
• Walter Haarmann

Key dates

• Filing date: Sep 13, 1979
• Grant date: Apr 7, 1981
• Expiry date: Sep 13, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/85
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1 is unsubstituted, mono-substituted or di-substituted piperidino, where the substituents are selected from the group consisting of methyl, hydroxymethyl, hydroxyl, phenyl and benzyl; PA0 R.sub.2 is hydrogen, methyl or benzyl; and PA0 R.sub.3 is hydrogen, halogen, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antiphlogistics and antithrombotics.