Organic compounds
US4261888A · kind A · utility
7Cited by
0References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 27, 1979 |
| Grant date | Apr 14, 1981 |
| Priority date | — |
| Expiry date | Nov 27, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/1016
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides polypeptides of formula I, EQU A-B-Gly-D-E I wherein A is Tyr or substituted Tyr, PA0 B is -Gly- or -(D)Ala-, PA0 D is, for example, Phe or MePhe and PA0 E is, for example, -Met-X, -Leu-X, -Nle-X, -Nva-X, -Ile-X, methioninesulhoxide-X, methioninesulphone-X wherein X is --NR'R" or --OR'" and each of R', R" and R'" independently signifies hydrogen or alkyl of 1 to 5 carbon atoms, which compounds possess pharmacological activity, for example, analgesic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.