Allergen-containing substances
US4261973A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1977 |
| Grant date | Apr 14, 1981 |
| Priority date | — |
| Expiry date | Aug 8, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention pertains to allergen-containing substances, methods of preparing the same and using the same as immunologically specific suppressants of the production of reaginic antibodies directed to the allergen in question. The allergen-containing substances can be characterized as covalent conjugates of the allergen molecules with non-immunogenic water-soluble polymers. The degree of conjugation is such that the conjugates are rendered tolerogenic as well as substantially non-allergenic and non-immunogenic. The new conjugates are useful for immunologically specific suppression of common allergies in mammals, including humans, which are mediated by reaginic antibodies of the IgE class.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.