Patent · US Expired

Enlarged hetero-ring prostacyclin analogs

US4262116A · kind A · utility

6Cited by
1References
13Claims
0Family size

Assignee

Inventor

Key dates

Filing dateAug 11, 1978
Grant dateApr 14, 1981
Priority date
Expiry dateAug 11, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/94
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Prostaglandin (PG.sub.1, derivatives having (1) a 5-keto feature, for example ##STR1## or (2) a 9-deoxy-5,9-epoxy feature together with a 4-halo or 5-hydroxy feature, for example ##STR2## or a 4,5-didehydro feature, for example in an enol ether of the formula ##STR3## said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.