Thio etianic acid derivatives
US4263289A · kind A · utility
35Cited by
1References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 31, 1979 |
| Grant date | Apr 21, 1981 |
| Priority date | — |
| Expiry date | Aug 31, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J31/006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain 16.beta.-methyl-3-oxoandrost-4-ene and 16.beta.-methyl-3-oxoandrosta-1,4-diene 17.beta.-thiocarboxylic acid esters are useful as anti-inflammatory steroids. These compounds are optionally substituted at the 6.alpha.-position with fluoro or chloro; optionally substituted at the 9.alpha. position with fluoro, chloro or bromo; substituted at the 11 position with a keto, a .beta.-hydroxy or a .beta.-chloro (the latter only when there is a 9.alpha.-chloro); and substituted with 17.alpha.-hydroxy (or an ester thereof).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.