Substituted 2-phenylamino-1,3-tetrahydro-2-pyrimidines and salts thereof

US4263300A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Helmut Stahle
• Herbert Koppe · Ingelheim am Rhein, DE
• Werner Kummer · Ingelheim am Rhein, DE
• Walter Kobinger · Wien, AT
• Christian Lillie · Wien, AT
• Ludwig Pichler · Wien, AT

Key dates

• Filing date: Jul 17, 1979
• Grant date: Apr 21, 1981
• Expiry date: Jul 17, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to 2-phenylamino-1,3-tetrahydro-2-pyrimidines of general formula ##STR1## wherein R is a radical selected from the group consisting of ##STR2## EQU --CH.sub.2 --CH.dbd.CH.sub.2, --CH.sub.2 --CH.dbd.CH--CH.sub.3, and --CH.sub.2 --C(CH.sub.3).dbd.CH.sub.2, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds, including the salts, are useful as bradycardiacs.