Patent · US Expired

7.alpha.-Methoxy-7.beta.-(1,3-dithietane-2-carboxamido)cephalosporanic acid derivatives

US4263432A · kind A · utility

13Cited by
6References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1978
Grant dateApr 21, 1981
Priority date
Expiry dateJun 7, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D339/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to novel 7.alpha.-methoxycephalosporin derivatives having at the 7.beta.-position an amido group acylated by a 1,3-dithietane carboxylic acid residue and to 7.beta.-isothiazolylthioacetamido-7.alpha.-methoxycephalosporins having antibacterial activity by themselves and, as the case may be, capable of being converted into the aforesaid 7.alpha.-methoxycaphalosporin derivatives. The compounds of this invention exhibit excellent antibacterial activity and are particularly effective against gram negative bacteria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.