Patent · US Expired

DNA Joining method

US4264731A · kind A · utility

50Cited by
0References
10Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 21, 1978
Grant dateApr 28, 1981
Priority date
Expiry dateApr 21, 1998

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/849
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A selected portion of DNA molecules having reactant ends which are capable of being joined in a ligase catalyzed reaction are pretreated so a to remove the 5'-terminal phosphate groups. Such a treatment reduces the frequency of joining an undersired combination and enhances the frequency of joining the desired combination.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.