Method for typing human leukocyte antigens
US4265873A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 3, 1978 |
| Grant date | May 5, 1981 |
| Priority date | — |
| Expiry date | Jul 3, 1998 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/554
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cellular method for typing lymphocyte defined human leukocyte antigens by utilizing human blood leukocytes which have been sensitized to proliferatively respond to the secondary stimulus of the leukocyte antigens to which they have been sensitized. The sensitization is accomplished by incubating, in vitro, in a mixed leukocyte culture, the leukocytes to be sensitized with leukocytes differing by only a single major histocompatibility complex haplotype or a single HLA-D antigenic determinant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.