Patent · US Expired

Method for typing human leukocyte antigens

US4265873A · kind A · utility

3Cited by
1References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 3, 1978
Grant dateMay 5, 1981
Priority date
Expiry dateJul 3, 1998

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/554
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A cellular method for typing lymphocyte defined human leukocyte antigens by utilizing human blood leukocytes which have been sensitized to proliferatively respond to the secondary stimulus of the leukocyte antigens to which they have been sensitized. The sensitization is accomplished by incubating, in vitro, in a mixed leukocyte culture, the leukocytes to be sensitized with leukocytes differing by only a single major histocompatibility complex haplotype or a single HLA-D antigenic determinant.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.