Propionamidoxime derivatives

US4265911A · kind A · utility

Assignee

• Synthelabo · FR

Inventors

• Henry Najer · Paris, FR
• Daniel Obitz · Fontenay-aux-Roses, FR

Key dates

• Filing date: Oct 9, 1979
• Grant date: May 5, 1981
• Expiry date: Oct 9, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C259/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Propionamidoxime derivatives which are compounds of formula (I) ##STR1## in which A is a tetrahydronaphthyl or dihydronaphthyl radical and their pharmaceutically acceptable salts are valuable for treatment of the central nervous system and depression. The above compounds are prepared by reacting the nitrile (II) ##STR2## with hydroxylamine hydrochloride.