Process for the manufacture of ketones

US4266066A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Werner Spielmann · Burgstetten, DE
• Georg Schaeffer

Key dates

• Filing date: Nov 26, 1979
• Grant date: May 5, 1981
• Expiry date: Nov 26, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/46
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Ketones are prepared by reacting carboxylic acid halides, in particular carboxylic acid chlorides, with aluminum-alkyl compounds, optionally in the presence of an aluminum trihalide, in methylene chloride as the solvent, at a temperature between about 20.degree. and about 100.degree. C., preferably between about 30.degree. and about 60.degree. C., more preferably of about 40.degree. C. which is the reflux temperature of the methylene chloride. When operating at a temperature above approximately 40.degree. C., pressure higher than atmospheric is applied. The reaction mixture is worked up in usual manner, suitably by decomposition with water followed by distillation.