Preparation of 4-fluoro-3-phenoxy-toluene

US4266082A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reimer Collin · Wuppertal, DE
• Hans-Joachim Diehr · Wuppertal, DE
• Uwe Friesnitz · Finsterwalde, DE

Key dates

• Filing date: Aug 17, 1979
• Grant date: May 5, 1981
• Expiry date: Aug 17, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C43/29
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of 4-fluoro-3-phenoxy-toluene of the formula ##STR1## comprising reacting 3-bromo-4-fluoro-toluene, of the formula ##STR2## with potassium phenolate, or with sodium phenolate in the presence of a potassium salt, in a diluent in the presence of copper as catalyst at a temperature between about 120.degree. and 180.degree. C.