Process for the preparation of N-(1'-alkoxycarbonylethyl)-2,6-dialkylanilines
US4267356A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1980 |
| Grant date | May 12, 1981 |
| Priority date | — |
| Expiry date | Jun 9, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C227/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is described for the preparation of N-(1'-alkoxycarbonylethyl)-2,6-dialkylanilines of the formula ##STR1## in which R.sub.1 and R.sub.2 are each methyl or ethyl and R.sub.3 is an alkyl group having 1 to 4 carbon atoms, this process being based on the reaction of a corresponding 2,6-dialkylaniline with a corresponding alkyl 2-chloropropionate or alkyl 2-bromopropionate. The process is carried out by carrying out the reaction of the 2,6-dialkylaniline with the 2-halogenopropionic acid ester at 110.degree.-130.degree. C. in the presence of an alkali metal iodide as the catalyst, and of an alkali metal carbonate or alkali metal bicarbonate as an acid acceptor, in excess 2,6-dialkylaniline as the solvent, removing, by distillation, the water formed during the reaction and working up the organic phase, which is obtained after adding water and separating the phases, by distillation. The N-(1'-alkoxycarbonylethyl)-2,6-dialkylanilines of the above formula which can be prepared by this process are valuable intermediates for the preparation of compounds having a pesticidal action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.