5,6,7,8-Tetrahydronaphthalene hypotensive agents
US4267373A · kind A · utility
8Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1977 |
| Grant date | May 12, 1981 |
| Priority date | — |
| Expiry date | Nov 14, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
5,6,7,8-Tetrahydronaphthalenes having the structure ##STR1## and the pharmaceutically acceptable salts thereof, are useful as blood pressure lowering agents. In the above formula R.sub.1 can be hydrogen or alkyl; R.sub.2 is alkyl; R.sub.3 and R.sub.4 can each be hydrogen, hydroxyl, alkoxy, or arylalkoxy, but both cannot be hydroxyl. Those compounds wherein at least one of R.sub.3 and R.sub.4 is other than hydrogen are novel, and constitute a part of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.