Hexahydro-1,4-oxazepines, their preparation, and drugs containing these compounds

US4269833A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Jörg Treiber · Münstermaifeld, DE
• Dieter Lenke · Ludwigshafen, DE
• Wolfgang Worstmann · Havelsee, DE

Key dates

• Filing date: Dec 31, 1979
• Grant date: May 26, 1981
• Expiry date: Dec 31, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel hexahydro-1,4-oxazepines of the general formula I ##STR1## where R.sup.1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms, PA1 R.sup.2 is alkyl of 1 to 4 carbon atoms and PA1 R.sup.3 and R.sup.4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy. The compounds may be used for the pharmacotherapy of pain of various geneses.