Macromolecular environment control in specific receptor assays
US4275149A · kind A · utility
815Cited by
6References
46Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 24, 1978 |
| Grant date | Jun 23, 1981 |
| Priority date | — |
| Expiry date | Nov 24, 1998 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/971
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method and compositions are provided for performing protein binding assays involving a homologous pair consisting of ligand and receptor for the ligand. The method employs a label conjugated to a member of said homologous pair and a uniformly dispersed discontinuous phase of discrete particles in a continuous aqueous phase, where the discrete particles create microenvironments which allow for discrimination between the label associated with the particle--in a discontinuous phase--and the label in the continuous phase. Various conjugates and particles are provided which find use in the subject method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.