Combinations of penicillanic acid 1,1-dioxide with 7-(D-2-[4-ethylpiperazin-2,3-dione-1-carboxamido]-2-[4-hydroxyphenyl]ace tamido)-3-([1-methyl-5-tetrazolyl]thiomethyl)-3-desacetoxymethylcephalosp oranic acid
US4276285A · kind A · utility
3Cited by
2References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 5, 1979 |
| Grant date | Jun 30, 1981 |
| Priority date | — |
| Expiry date | Mar 5, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Penicillanic acid 1,1-dioxide, pharmaceutically-acceptable salts thereof, and esters thereof readily hydrolyzable in vivo, enhance the antibacterial effectiveness of 7-(D-2-[4-ethylpiperazin-2,3-dione-1-carboxamido]-2-[4-hydroxyphenyl]aceta mido)-3-([1-methyl-5-tetrazolyl]thiomethyl)-3-desacetoxymethylcephalosporan ic acid, and salts thereof, against many beta-lactamase producing bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.