Process for the manufacture of para-tert.butylbenzaldehyde and its derivatives which are halogen-substituted at the nucleus

US4277421A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Franz Landauer · Frankfurt am Main, DE
• Georg Schaeffer

Key dates

• Filing date: Nov 14, 1979
• Grant date: Jul 7, 1981
• Expiry date: Nov 14, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C45/85
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

p-tert.Butylbenzaldehyde and the derivatives thereof which are halogen-substituted at the nucleus are prepared by bromination of p-tert.butyltoluene and the derivatives thereof which are correspondingly halogen-substituted at the nucleus under side-chain halogenation conditions until the benzal bromide is obtained which is then saponified. Practically no undesired bromination at the nucleus or the tert.butyl group takes place. The products obtained are valuable intermediates for the manufacture of pharmaceutical agents, plant protecting agents and dyestuffs.