Patent · US Expired

Antibiotic and use thereof

US4277478A · kind A · utility

3Cited by

0References

8Claims

0Family size

Assignee

Ciba-Geigy · US

Inventors

Hans Zahner · Quakenbrück, DE
Hannelore Drautz · Lingen (Ems), DE
Walter Keller · Oldsmar, US

Key dates

Filing date	May 21, 1979
Grant date	Jul 7, 1981
Priority date	—
Expiry date	May 21, 1999

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/18
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to the new antibiotic Lysolipin including two components X and I, and derivatives thereof. Lysolipin is formed when the strain Streptomyces violaceoniger (Waksman et Curtis) Waksman et Henrici Tu 96, which strain has been deposited under the reference NRRL 8097 at the Northern Regional Laboratory, U.S. Department of Agriculture, Peoria, Illinois, is cultured in a nutrient medium. The structural formulae of the 2 components are ##STR1## Lysolipin I and X and their derivatives have antibacterial activity and are effective against yeast - like fungi, such as Candida albicans. Their antibiotic action probably depends on an inhibition of the cell wall synthesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.