Preparation of 5-hydroxymethylimidazoles

US4278801A · kind A · utility

Assignee

• BASF SE

Inventors

• Uwe Kempe · Schifferstadt, DE
• Toni Dockner
• Anton Frank · Ludwigshafen, DE
• Helmut Karn · Ludwigshafen, DE

Key dates

• Filing date: Feb 8, 1980
• Grant date: Jul 14, 1981
• Expiry date: Feb 8, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/64
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the manufacture of 5-hydroxymethylimidazoles by reaction of an imidazole with formaldehyde or an oligomer of formaldehyde in aqueous hydrochloric acid solution containing from 5 to 18% by weight of hydrogen chloride, at from 80.degree. to 160.degree. C., if desired in a closed system under pressure, followed by isolation in the form of its hydrochloride of the 5-hydroxymethylimidazole obtained.