Method of preparing a 3-alkoxy-2-alkyl-propionic acid ester derivative and intermediate therefor
US4278808A · kind A · utility
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6Claims
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Key dates
| Filing date | Sep 14, 1978 |
| Grant date | Jul 14, 1981 |
| Priority date | — |
| Expiry date | Sep 14, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C69/708
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-Alkoxy-2-alkyl-propionic acid derivatives are prepared by catalytic hydrogenation of the acrylic acid analogs. The latter are obtained by CO treatment of lower alkyl esters of alkanoic acids having 3-6 carbon atoms in the presence of alkali metal methylate and condensation of the resulting 2-formylalkanoic acids or their alkali metal enolates with compounds of the formula X--(CH.sub.2).sub.m --Z wherein X is Cl, Br, or OH, and Z is Cl, Br, I, alkyl- or arylsulfonyl, or OH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.