Process for preparing 2-isocyanatoalkyl esters of organic carboxylic acids
US4278809A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 15, 1977 |
| Grant date | Jul 14, 1981 |
| Priority date | — |
| Expiry date | Jun 15, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Isocyanatoalkyl esters of organic carboxylic acids are prepared by reacting (a) an aqueous solution of a 2-oxazoline with (b) an organic solution of phosgene dissolved in a water-immiscible organic solvent in the presence of (c) a hydrochloric acid acceptor. As an example, 2-isocyanatoethyl methacrylate was prepared by concurrently blending an aqueous stream of 2-isopropenyl-2-oxazoline, a methylene chloride stream of phosgene and an aqueous stream of sodium hydroxide at a temperature of from about 0.degree. C. to about 10.degree. C. The reaction rate is very high and the reaction is essentially complete upon blending the reactants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.