Patent · US Expired

N-Formyl leurosine derivatives in a dosage form effective for treating lymphoid leukemia

US4279816A · kind A · utility

0Cited by
1References
2Claims
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Assignee

Inventors

Key dates

Filing dateFeb 5, 1975
Grant dateJul 21, 1981
Priority date
Expiry dateFeb 5, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

New leurosine derivatives of the general formula (1), ##STR1## wherein R stands for hydrogen or formyl, or pharmaceutically acceptable acid addition salts thereof were prepared by oxidizing leurosine or an acid addition salt thereof, optionally formylating the thus-obtained product and then separating, and, if desired, converting any of the free bases into its acid addition salt.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.