Amides useful as brain imaging agents
US4279887A · kind A · utility
22Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 29, 1978 |
| Grant date | Jul 21, 1981 |
| Priority date | — |
| Expiry date | Nov 29, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain radioiodine containing amides useful as brain imaging agents are disclosed. The compounds of the subject invention are represented by the formula ##STR1## wherein I is a radioisotope of iodine with I-123 being preferred, R.sub.1 and R.sub.2 are the same or different and are selected from the grooup consisting of hydrogen, hydroxy, alkyl, aryl, substituted aryl, aralkyl, anilino and carbamoylmethyl or R.sub.1 and R.sub.2 taken together with the nitrogen to which they are attached form a 5- or 6-membered ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.