2-(Nuclearly-substituted)benzylpyrrolidines

US4279918A · kind A · utility

Assignee

• Byk Gulden Lomberg Chemische Fabrik GmbH · DE

Inventors

• Klaus Eistetter · Konstanz, DE
• Hartmann Schaefer
• Heinz-Gunter Menge

Key dates

• Filing date: Jul 27, 1977
• Grant date: Jul 21, 1981
• Expiry date: Jul 27, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/24
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

2-Benzylpyrrolidines bearing from 1 to 4 nuclear substituents on the benzyl ring are pharmacologically active, particularly on the CNS, on blood pressure and on pain sensation for warm-blooded animals. They are synthesized, e.g., by reducing appropriate 2-benzylpyrrolidines and are formulated into medicament compositions according to established conventional techniques.