Technetium-99m generators
US4280053A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1978 |
| Grant date | Jul 21, 1981 |
| Priority date | — |
| Expiry date | Jun 2, 1998 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G1/0005
- WIPO fieldEngines, pumps, turbines
- WIPO sectorMechanical engineering
Abstract
A Technetium-99m generator has a matrix having a compound of molybdenum-99 bound into or forming the matrix, the compound of the molybdenum-99 being substantially insoluble in an eluant which can be used in a radiopharmaceutical and the molybdenum compound permitting diffusion of technetium-99m therethrough and elution therefrom. The molybdenum compound can be a monomolybdate, an isopolymolybdate or a heteropolymolybdate and zirconium molybdate is preferred although other cation molybdates may be used. Methods of preparation of the generator include dissolving irradiated molybdenum trioxide in alkaline solution and precipitating the molybdate at a selected pH and packing the precipitate in finely divided form into a column. Alternatively the generator may be formed from a non-radioactive, molybdenum compound and activated later when desired by passing a solution of a compound of molybdenum-99 through the column.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.