Crosslinked collagen-mucopolysaccharide composite materials

US4280954A · kind A · utility

Assignee

• Massachusetts Institute of Technology · US

Inventors

• Ioannis V. Yannas · Newton, US
• Philip L. Gordon · Lexington, US
• Chor Huang · Avon Lake, US
• Frederick H. Silver · Bangor, US
• John Burke · Cortland, US

Key dates

• Filing date: Apr 16, 1979
• Grant date: Jul 28, 1981
• Expiry date: Apr 16, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2310/00365
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Composite materials are disclosed which are formed by contacting collagen with a mucopolysaccharide and subsequently covalently crosslinking the resultant polymer. These composite materials have a balance of mechanical, chemical and physiological properties which make them useful in surgical sutures and prostheses of controlled biodegradability (resorption) and controlled ability to prevent development of a foreign body reaction, and many are also useful in applications in which blood compatibility is required.